The ocular biometric and corneal topographic characteristics of high-anisometropic adults in Taiwan.

BACKGROUND To investigate the difference of ocular biometric and corneal topographic characteristics between the two eyes in high anisometropes with difference of 4 D or more in spherical component. METHODS Fifty-one young anisometropic men were collected. Detailed ocular examinations, including cycloplegic autorefraction, best-corrected visual acuity, intraocular pressure, A-scan, and Orbscan topography were done and recorded. The comparisons between two eyes were performed and the correlations between different ocular parameters were evaluated. RESULTS The mean axial length in the more myopic/less hyperopic eye was longer than that in the less myopic/more hyperopic eye [difference 1.8 mm, 95% confidence interval (CI) 1.6-2.0 mm, p < 0.001]. The mean thinnest corneal thickness in the more myopic/less hyperopic eye was an average of 4.0 μm thicker than that in the other eye (95% CI 1.2-6.8 μm, p = 0.007). The mean anterior chamber depth in the more myopic/less hyperopic eye was an average of 0.05 mm (95% CI 0.02-0.07 mm, p < 0.001) more than that in the other eye. The curvature and size of cornea were not significantly different. CONCLUSION The anterior chamber depth is deeper, axial length is longer, and thinnest corneal thickness is thicker in the more myopic/less hyperopic eye of high-anisometropic patients. Anisometropic eyes provide the chance to understand the biometric changes of eyeball with different refractive statuses in the same person. Such information is helpful for us to calculate the intraocular lenses power in cataract surgery and to do the surgical planning for corneal refractive surgery in eyes of different refractive power.